SCHEMBL6795028

SCHEMBL6795028

CC(C)c1cccc(-c2ccccc2C(=O)Nc2ccnc(CCN(C(=O)OC(C)(C)C)c3ccccc3)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.41
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
SMO Q99835 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
F2 P00734 2/20 0.38
ALDH1A1 P00352 2/20 0.38
FADS1 O60427 1/20 0.38
AURKA O14965 1/20 0.38
RPS6KB1 P23443 1/20 0.38
ITGB1 P05556 1/20 0.37
ITGA4 P13612 1/20 0.37
TRPV4 Q9HBA0 1/20 0.37
NPY2R P49146 7/20 0.37
MTTP P55157 2/20 0.37
HTT P42858 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6795030 0.90 SMO (0.41) BACE1GAASMOF2ALDH1A1
SCHEMBL6796397 0.85 SMO (0.41) KDM4EGAASMOL3MBTL1F2
SCHEMBL6795031 0.85 SMO (0.40) KDM4EGAASMOL3MBTL1F2
SCHEMBL6796112 0.82 MEN1 (0.41) BACE1F2AURKARPS6KB1TRPV4
SCHEMBL6795007 0.80 SMO (0.48) KDM4EGAASMOL3MBTL1F2
SCHEMBL6645327 0.80 ALDH1A1 (0.43) BACE1KDM4EGAAF2ALDH1A1
SCHEMBL6648457 0.80 F2 (0.40) BACE1SMOL3MBTL1F2ALDH1A1
SCHEMBL6792911 0.79 SMO (0.47) KDM4EGAASMOL3MBTL1F2
SCHEMBL6794007 0.78 L3MBTL1 (0.44) KDM4EGAASMOL3MBTL1ALDH1A1
SCHEMBL6645210 0.78 F2 (0.37) BACE1F2AURKARPS6KB1ITGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 BACE1 320/4885KDM4E 3114/4885GAA 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.