Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 7/20 | 0.54 |
| ▸ | CA9 | Q16790 | 7/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998250 | 0.86 | STS (0.51) | STSCA2CA9CA1 | |
| SCHEMBL3643483 | 0.76 | CA2 (0.50) | STSCA2CA9CA1MAPT | |
| SCHEMBL29964032 | 0.76 | CHRM1 (0.44) | MAPTHPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6795080 | 0.76 | CA2 (0.58) | STSCA2CA9CA1HPGD | |
| SCHEMBL2914928 | 0.75 | DRD1 (0.58) | CA2CA1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL29633762 | 0.75 | DRD1 (0.58) | CA2CA1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9563396 | 0.75 | ALDH1A1 (0.49) | MAPTHPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9563395 | 0.75 | MAPT (0.49) | CA2CA9CA1MAPTHPGD | |
| SCHEMBL2141556 | 0.74 | ALDH1A1 (0.52) | MAPTHPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2720506 | 0.73 | ALDH1A1 (0.70) | MAPTHPGDSMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |