Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21257991 | 0.77 | KMT2A (0.52) | GAAALDH1A1TACR1ATMKDM4E | |
| SCHEMBL6797003 | 0.70 | GRIN2B (0.38) | GRIN2B | |
| SCHEMBL6803849 | 0.70 | ALDH1A1 (0.70) | GAAALDH1A1CYP2A13ATMKDM4E | |
| SCHEMBL7424735 | 0.69 | ALDH1A1 (0.64) | ALDH1A1CYP2A13ATMKDM4ELMNA | |
| SCHEMBL6804350 | 0.69 | GRIN2B (0.43) | GAAALDH1A1GRIN2BLMNAHTT | |
| SCHEMBL21257992 | 0.69 | KDM4E (0.55) | GAAALDH1A1TACR1KDM4ELMNA | |
| SCHEMBL30341108 | 0.68 | ALDH1A1 (0.73) | GAAALDH1A1CYP2A13ATMKDM4E | |
| SCHEMBL20936791 | 0.67 | ALDH1A1 (0.51) | ALDH1A1TACR1CYP2A13ATMKDM4E | |
| SCHEMBL20937474 | 0.67 | ALDH1A1 (0.51) | ALDH1A1TACR1CYP2A13ATMKDM4E | |
| SCHEMBL6943859 | 0.67 | ATM (0.49) | GAAALDH1A1CYP2A13RORCATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821964-B2 | FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH MONOCYTE ACCUMULATION, LYMPHOCYTE ACCUMULATION OR LEUCOCYTE ACCUMULATION | PFIZER INC | 2004-11-23 | — | — | US | disclosed |