SCHEMBL7424735

SCHEMBL7424735

O=CN1CCN(Cc2ccccc2F)CC1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.64
CYP2A13 Q16696 1/20 0.60
POLB P06746 2/20 0.56
KDM4E B2RXH2 5/20 0.56
LMNA P02545 3/20 0.56
HTT P42858 2/20 0.56
KMT2A Q03164 7/20 0.55
MEN1 O00255 5/20 0.54
ATM Q13315 3/20 0.54
MAPK1 P28482 1/20 0.54
ALDH3A1 P30838 1/20 0.51
GPR183 P32249 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7424299 0.95 ALDH1A1 (0.68) ALDH1A1CYP2A13POLBKDM4ELMNA
SCHEMBL16226380 0.87 ALDH1A1 (0.81) ALDH1A1CYP2A13POLBKDM4ELMNA
SCHEMBL7425132 0.80 CXCR3 (0.53) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL3262128 0.80 ALDH1A1 (0.96) ALDH1A1CYP2A13POLBKDM4ELMNA
SCHEMBL7369286 0.79 MPO (0.46) ALDH1A1KDM4EHTTKMT2AATM
SCHEMBL7418676 0.79 SIGMAR1 (0.67) ALDH1A1CYP2A13KDM4ELMNAHTT
SCHEMBL2321124 0.79 KMT2A (0.67) ALDH1A1CYP2A13KDM4ELMNAHTT
SCHEMBL22365062 0.79 CYP2A13 (0.56) ALDH1A1CYP2A13POLBKDM4ELMNA
SCHEMBL28552309 0.79 ATM (0.58) ALDH1A1CYP2A13POLBKDM4ELMNA
SCHEMBL16226719 0.79 ALDH1A1 (0.68) ALDH1A1CYP2A13POLBKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997044334-A2 NOVEL PIPERAZINE OR HOMOPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THEIR PREPARATION EGIS Gyógyszergyár Rt. (HU) 1997-11-27 WO disclosed