Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.60 |
| ▸ | VNN1 | O95497 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993780 | 1.00 | MAPT (0.64) | MAPTGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL25638635 | 0.92 | MAPT (0.55) | MAPTGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL5992317 | 0.86 | LOXL2 (0.63) | CACNA1BALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10078294 | 0.86 | LOXL2 (0.63) | CACNA1BALDH1A1KDM4ECA12CA1 | |
| SCHEMBL5669873 | 0.86 | MAPT (0.82) | MAPTGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL10055019 | 0.86 | MAPT (0.82) | MAPTGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL1844199 | 0.86 | MAPT (0.82) | MAPTGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL28248607 | 0.86 | MAPT (0.55) | MAPTGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL5436758 | 0.84 | MAOA (0.52) | MAPTGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL934511 | 0.82 | VNN1 (0.58) | MAPTGAARAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679541-B | Preparation method and application of metal organic ternary cyclic compound | 大连理工大学 | 2022-03-18 | — | — | CN | claimed |
| CN-112679541-A | Preparation method and application of metal organic ternary cyclic compound | 大连理工大学 | 2021-04-20 | — | — | CN | claimed |
| CN-112679541-B | Preparation method and application of metal organic ternary cyclic compound | 大连理工大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-112679541-A | Preparation method and application of metal organic ternary cyclic compound | 大连理工大学 | 2021-04-20 | — | — | CN | disclosed |
| US-7576200-B2 | Diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-08-18 | — | — | US | disclosed |
| US-20080281092-A1 | Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use | AVENTIS PHARMA DEUTSCHLAND GMBH | 2008-11-13 | — | — | US | disclosed |
| US-5843333-A | Metallo organo liquid crystals in a polymer matrix | SNIARICERCHE S.C.P.A (IT) | 1998-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281092-A1 | Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use | QDPR, NDUFB6, NDUFB7 | MAPT 4430/4885GAA 897/4885RAB9A 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.