Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 7/20 | 0.59 |
| ▸ | MTTP | P55157 | 6/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605815 | 0.89 | APOB (0.63) | APOBMTTPRXFP1HTTPPARG | |
| SCHEMBL6799012 | 0.89 | APOB (0.66) | APOBMTTPRXFP1HTTPPARG | |
| Hydrochloric Acid SCHEMBL7607266 | 0.88 | APOB (0.65) | APOBMTTPRXFP1HTTPPARG | |
| SCHEMBL7605826 | 0.87 | HTT (0.64) | HTTKCNK3KCNK9ALDH1A1KDM4E | |
| SCHEMBL7611559 | 0.86 | CHRNB2 (0.68) | HTTKCNK3KCNK9ALDH1A1KDM4E | |
| SCHEMBL7613563 | 0.85 | APOB (0.59) | APOBMTTPRXFP1HTTPPARG | |
| SCHEMBL7605511 | 0.84 | APOB (0.56) | APOBMTTPRXFP1HTTKCNK3 | |
| SCHEMBL7612786 | 0.84 | L3MBTL1 (0.64) | HTTNR1H4KCNK3KCNK9ALDH1A1 | |
| SCHEMBL31393757 | 0.84 | CHRNB2 (0.71) | APOBMTTPHTTALDH1A1GAA | |
| SCHEMBL2104422 | 0.84 | RAB9A (0.69) | RXFP1HTTPPARGPPARDNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | APOB 45/4885MTTP 1/4885RXFP1 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.