Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554935 | 0.76 | SLC18A3 (0.32) | CYP2C9SLC18A3GBA1CYP2D6 | |
| SCHEMBL4893829 | 0.74 | CYP1A2 (0.35) | CYP3A4CYP2C9LMNAMEN1KMT2A | |
| SCHEMBL15282149 | 0.74 | CYP1A2 (0.35) | CYP3A4CYP2C9LMNAMEN1KMT2A | |
| SCHEMBL4907271 | 0.73 | ORAI1 (0.40) | CYP2C9SLC18A3GBA1MEN1KMT2A | |
| Biphenyl SCHEMBL28424673 | 0.73 | CYP2D6 (0.49) | ESR1ESR2CYP3A4CYP2C9SLC18A3 | |
| SCHEMBL12160731 | 0.72 | ACHE (0.48) | SLC18A3CHRM3 | |
| Phenol SCHEMBL22542897 | 0.71 | ESR2 (0.61) | ESR1ESR2CYP3A4CYP2C9SLC18A3 | |
| Phenol SCHEMBL8771544 | 0.71 | ESR2 (0.61) | ESR1ESR2CYP3A4CYP2C9SLC18A3 | |
| SCHEMBL4899672 | 0.69 | LMNA (0.39) | CYP3A4CYP2C9LMNAL3MBTL1KMT2A | |
| Methyl Alcohol SCHEMBL6903083 | 0.69 | APOBEC3A (0.40) | CYP3A4CYP2C9SLC18A3CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242639-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242639-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | PLA2G4C, PLA2G4B, PLA2G5 | ESR1 2982/4885ESR2 1940/4885CYP3A4 3103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.