SCHEMBL679965

SCHEMBL679965

Cc1ccc(N(C)c2ccc(-c3ccc(N(C)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
TSHR P16473 2/20 0.57
ACHE P22303 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 2/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CES1 P23141 1/20 0.40
CHKA P35790 3/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
DHFR P00374 1/20 0.39
CHRNA7 P36544 1/20 0.39
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2C19 P33261 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37
NOTUM Q6P988 1/20 0.37
APP P05067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13289018 1.00 ALDH1A1 (0.57) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL10042846 1.00 ALDH1A1 (0.57) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL13242008 0.93 ALDH1A1 (0.50) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL12379576 0.93 ALDH1A1 (0.50) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL812498 0.91 ALDH1A1 (0.67) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL15854781 0.91 ALDH1A1 (0.67) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL22083898 0.91 ALDH1A1 (0.67) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL517128 0.91 ALDH1A1 (0.67) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL12249808 0.91 ALDH1A1 (0.48) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL2623413 0.91 CHKA (0.49) ALDH1A1TSHRACHETDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020121979-A1 LIQUID-CRYSTAL ALIGNMENT AGENT, LIQUID-CRYSTAL ALIGNMENT FILM, AND LIQUID-CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-06-18 WO disclosed
WO-2019182072-A1 POLYUREA COPOLYMER, LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-18 US disclosed
US-8247800-B2 Triarylamine containing polymers and electronic devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-21 US disclosed
US-20120010359-A1 SALICYLATE SUBSTITUTED CONJUGATED POLYMERS AND DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
US-8052894-B2 Salicylate substituted conjugated polymers and devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-08 US disclosed
US-8034882-B2 Biscarbazol-9-yl-substituted triarylamine-containing polymers and electronic devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-11 US disclosed
US-20110105711-A1 CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS AND CONJUGATED OLIGOMERS OR POLYMERS BASED THEREON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-05 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-7893160-B2 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-22 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-7781757-B2 Organic semiconductor material, organic semiconductor element and field effect transistor using the same SANYO ELECTRIC CO., LTD. (JP) 2010-08-24 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 US disclosed
US-20080011353-A1 Triarylamine Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-17 US disclosed
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon DOW GLOBAL TECHNOLOGIES INC. 2007-05-10 US disclosed
US-20070045618-A1 Organic semiconductor material, organic semiconductor element and field effect transistor using the same SANYO ELECTRIC CO., LTD. (JP) 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105711-A1 CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS AND CONJUGATED OLIGOMERS OR POLYMERS BASED THEREON THEM6, PCNA, PARG ALDH1A1 2935/4885TSHR 3371/4885ACHE 1644/4885
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES NAT1, SAT1, RIF1 ALDH1A1 529/4885TSHR 3228/4885ACHE 3463/4885
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES NAT1, AHR, AR ALDH1A1 2225/4885TSHR 627/4885ACHE 4134/4885
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon THEM6, PCNA, PARG ALDH1A1 2938/4885TSHR 4086/4885ACHE 1065/4885
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices TLR9, TLR5, TLR1 ALDH1A1 267/4885TSHR 4693/4885ACHE 2611/4885
US-20070045618-A1 Organic semiconductor material, organic semiconductor element and field effect transistor using the same AS3MT, TST, ALK ALDH1A1 3283/4885TSHR 74/4885ACHE 1474/4885
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices PYM1, KCNMB4, BRD9 ALDH1A1 2994/4885TSHR 754/4885ACHE 3484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.