Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680012 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TDP1METAP2METAP1MAPT | |
| SCHEMBL9056306 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TDP1METAP2METAP1MAPT | |
| SCHEMBL27975177 | 0.86 | MEN1 (0.44) | ALDH1A1TDP1METAP2METAP1L3MBTL1 | |
| SCHEMBL31272384 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TDP1METAP2METAP1MAPT | |
| SCHEMBL5970722 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL5970217 | 0.77 | PGR (0.42) | ALDH1A1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL2879497 | 0.77 | METAP2 (0.60) | ALDH1A1TDP1METAP2METAP1MAPT | |
| SCHEMBL10594626 | 0.76 | ALPL (0.39) | ALDH1A1TDP1MAPTHTR6KMT2A | |
| SCHEMBL30011539 | 0.76 | ALPL (0.39) | ALDH1A1TDP1MAPTHTR6KMT2A | |
| SCHEMBL11025593 | 0.76 | HTR6 (0.48) | MAPTHTR6KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294139-B1 | POLYSILOXANE-POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-12-27 | — | — | EP | disclosed |
| EP-2238196-B1 | FLAME RETARDANT POLYIMIDE/POLYESTER-POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-12-18 | — | — | EP | disclosed |
| US-8389648-B2 | Polysiloxane-polycarbonate compositions, method of manufacture, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20110288214-A1 | POLYSILOXANE-POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-11-24 | — | — | US | disclosed |
| US-7994254-B2 | Polysiloxane-polycarbonate compositions, and related methods and articles | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-08-09 | — | — | US | disclosed |
| EP-2294139-A1 | POLYSILOXANE-POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC Innovative Plastics IP B.V. (NL) | 2011-03-16 | — | — | EP | disclosed |
| EP-2238196-A2 | FLAME RETARDANT POLYIMIDE/POLYESTER-POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC Innovative Plastics IP B.V. (NL) | 2010-10-13 | — | — | EP | disclosed |
| US-7732516-B2 | Flame retardant polyimide/polyester-polycarbonate compositions, methods of manufacture, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-06-08 | — | — | US | disclosed |
| US-20090318629-A1 | POLYSILOXANE-POLYCARBONATE COMPOSITIONS, AND RELATED METHODS AND ARTICLES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-12-24 | — | — | US | disclosed |
| WO-2009155013-A1 | POLYSILOXANE-POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009095825-A2 | FLAME RETARDANT POLYIMIDE/POLYESTER-POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (US) | 2009-08-06 | — | — | WO | disclosed |
| US-20090197999-A1 | Flame Retardant Polyimide/Polyester-Polycarbonate Compositions, Methods of Manufacture, and Articles Formed Therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-08-06 | — | — | US | disclosed |