Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 6/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795854 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6801223 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6796798 | 0.87 | KDM4E (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6796794 | 0.87 | KDM4E (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6796804 | 0.87 | KDM4E (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7008166 | 0.80 | HPGD (0.43) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6801836 | 0.76 | HPGD (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6801833 | 0.76 | HPGD (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6801830 | 0.76 | HPGD (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6299773 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044013-A1 | 1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix metalloproteinase (mmp) inhibitors | IBFB GMBH PRIVATES INSTITUT FUR BIOMEDIZINISCHE FORSCHUNG UND BERATUNG (DE) | 2004-03-04 | — | — | US | disclosed |
| EP-1349842-A1 | 1-DIMERCAPTOALKYLQUINAZOLIN-2,4(1H,3H)-DIONES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | IBFB GmbH Privates Institut für biomedizinische Forschung und Beratung (DE) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055507-A1 | 1-DIMERCAPTOALKYLQUINAZOLIN-2,4(1H,3H)-DIONES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | IBFB GMBH PRIVATES INSTITUT FÜR BIOMEDIZINISCHE FORSCHUNG UND BERATUNG (DE) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044013-A1 | 1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix metalloproteinase (mmp) inhibitors | MMP2, MMP3, MMP1 | ALDH1A1 517/4885MEN1 3691/4885KMT2A 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.