Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.63 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.63 |
| ▸ | TERT | O14746 | 7/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797692 | 0.85 | CYP3A4 (0.66) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL988001 | 0.82 | TERT (0.77) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL29612043 | 0.82 | TERT (0.77) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL6808412 | 0.81 | ADORA3 (0.58) | CYP3A4TERTALDH1A1MAPTHPGD | |
| SCHEMBL6618586 | 0.80 | TUBB4A (0.60) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL4649487 | 0.80 | CYP3A4 (0.76) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL6613755 | 0.79 | TERT (0.77) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL6612282 | 0.79 | TUBB4A (0.76) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL31438670 | 0.79 | TERT (0.67) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 | |
| SCHEMBL12556183 | 0.79 | CYP1A1 (0.51) | CYP1A2CYP3A4CYP2C19NCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-01 | — | — | US | disclosed |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | CYP1A2 3159/4885CYP3A4 3385/4885CYP2C19 3703/4885 |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | CYP1A2 3209/4885CYP3A4 3411/4885CYP2C19 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.