Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804299 | 0.85 | P2RX4 (0.46) | TSHRALDH1A1LMNA | |
| SCHEMBL27296626 | 0.74 | KDM4E (0.47) | GAAKDM4ETSHRSIRT3BRD4 | |
| SCHEMBL13212880 | 0.74 | ALDH1A1 (0.42) | GAAKDM4ETSHRSIRT3BRD4 | |
| SCHEMBL1966607 | 0.73 | TSHR (0.45) | GAAKDM4ETSHRADORA3ALDH1A1 | |
| SCHEMBL3623069 | 0.72 | TSHR (0.44) | GAAKDM4ETSHRADORA3ALDH1A1 | |
| SCHEMBL16334539 | 0.71 | TSHR (0.47) | GAAKDM4ETSHRSIRT3BRD4 | |
| SCHEMBL10607021 | 0.71 | TSHR (0.43) | GAAKDM4ETSHRADORA3ALDH1A1 | |
| SCHEMBL18828597 | 0.69 | MAOA (0.50) | GAAKDM4ETSHRBRD4MAOA | |
| SCHEMBL6948834 | 0.69 | GAA (0.33) | GAATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL20160512 | 0.69 | TSHR (0.51) | GAAKDM4ETSHRSIRT3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762303-B2 | OXIDIZING A DIHYDROPYRIDINE COMPOUND IN THE PRESENCE OF NITROUS ACID OR A NITRITE OR A BASE AND HYDROGEN PEROXIDE SOLUTION | FUJI PHOTO FILM CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| US-20020065420-A1 | Method for producing pyridine compounds | FUJIFILM CORPORATION (JP) | 2002-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065420-A1 | Method for producing pyridine compounds | NOX1, NOX5, NOX4 | GAA 1781/4885KDM4E 2650/4885TSHR 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.