Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803901 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTR2CMAPK1L3MBTL1 | |
| SCHEMBL16494700 | 0.85 | NPC1 (0.42) | ALDH1A1KDM4EDDB1CRBNHTR2C | |
| SCHEMBL27376459 | 0.81 | BRD4 (0.48) | ALDH1A1KDM4ECFTRL3MBTL1CYP1A2 | |
| SCHEMBL30806562 | 0.81 | BRD4 (0.48) | ALDH1A1KDM4ECFTRL3MBTL1CYP1A2 | |
| SCHEMBL2769306 | 0.81 | CASP1 (0.51) | ALDH1A1MAPK1CYP1A2CYP3A4DRD4 | |
| SCHEMBL6501814 | 0.80 | HTR2C (0.53) | ALDH1A1KDM4EHTR2CL3MBTL1CYP1A2 | |
| Quinoline SCHEMBL28271845 | 0.79 | HTR2C (0.41) | ALDH1A1KDM4EHTR2CMAPK1CFTR | |
| SCHEMBL6801884 | 0.79 | ROCK1 (0.47) | ALDH1A1KDM4EMAPK1L3MBTL1CYP1A2 | |
| SCHEMBL16494722 | 0.79 | DDB1 (0.49) | ALDH1A1KDM4EDDB1CRBNHTR2C | |
| SCHEMBL6644024 | 0.78 | TRPM5 (0.45) | ALDH1A1KDM4EL3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | ALDH1A1 2901/4885KDM4E 2600/4885DDB1 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.