Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804476 | 0.86 | CNR2 (0.52) | TSHRRECQLRAB9ASMN1; SMN2MAPT | |
| SCHEMBL6637186 | 0.85 | ALDH1A1 (0.47) | DHODHTSHRRECQLRAB9ASMN1; SMN2 | |
| SCHEMBL7724768 | 0.80 | IP6K1 (0.55) | DHODHTSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11187005 | 0.80 | DHODH (0.52) | DHODHTSHRRAB9ASMN1; SMN2MAPT | |
| Cyclohexane SCHEMBL8419079 | 0.79 | HNF4A (0.60) | TSHRRECQLRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30292805 | 0.79 | HNF4A (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL18759613 | 0.79 | HNF4A (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL3322530 | 0.78 | NPC1 (0.71) | DHODHTSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL28090800 | 0.78 | BCAT2 (0.64) | TSHRRECQLSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10692118 | 0.78 | NPC1 (0.71) | DHODHTSHRRAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | DHODH 4644/4885TSHR 1272/4885RECQL 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.