Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 4/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942315 | 0.97 | STAT3 (0.56) | STAT3STAT1TERTABCG2ALDH1A1 | |
| SCHEMBL4266558 | 0.89 | STAT3 (0.63) | STAT3STAT1TERTABCG2ALDH1A1 | |
| SCHEMBL31055740 | 0.88 | STAT3 (0.62) | STAT3STAT1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL585528 | 0.88 | STAT3 (0.62) | STAT3STAT1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9590030 | 0.87 | STAT3 (0.60) | STAT3STAT1TERTABCG2ALDH1A1 | |
| SCHEMBL2948398 | 0.86 | STAT3 (0.60) | STAT3STAT1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8996959 | 0.86 | STAT3 (0.59) | STAT3STAT1TERTABCG2ALDH1A1 | |
| SCHEMBL585368 | 0.85 | STAT3 (0.45) | STAT3STAT1TERTABCG2MAPT | |
| SCHEMBL17687652 | 0.85 | STAT3 (0.57) | STAT3STAT1TERTKDM4EMEN1 | |
| SCHEMBL498495 | 0.84 | TERT (0.51) | TERTABCG2ALDH1A1HSD17B10TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305317-B1 | DIHYDROPORPHYRIN DERIVATIVES AND THEIR USES | ANULM ASS NATAISE POUR L UTILI (FR) | 2004-09-15 | — | — | EP | disclosed |
| US-20040022734-A1 | Dihydroporphyrin derivatives and their uses | ANNULM, ASSOCIATION NANTAISE POUR L'UTILISATION DE LA LUMIERE EN MEDECINE (FR) | 2004-02-05 | — | — | US | disclosed |
| EP-1305317-A1 | DIHYDROPORPHYRIN DERIVATIVES AND THEIR USES | Anulm Association Nataise pour l'Utilisation de la Lumière en Medicine (FR) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010173-A1 | DIHYDROPORPHYRIN DERIVATIVES AND THEIR USES | ANULM ASSOCIATION NATAISE POUR L'UTILISATION DE LA LUMIERE EN MEDECINE (FR) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040022734-A1 | Dihydroporphyrin derivatives and their uses | PPOX, PPIF, DHPS | STAT3 2489/4885STAT1 4379/4885TERT 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.