Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427571 | 0.85 | ALDH1A1 (0.57) | SMN1; SMN2MYCLCKFYNALDH1A1 | |
| SCHEMBL30832923 | 0.84 | MCL1 (0.58) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10058709 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2MYCLCKFYNALDH1A1 | |
| SCHEMBL6808918 | 0.81 | AKR1C3 (0.55) | SMN1; SMN2LCKFYNALDH1A1KDM4E | |
| SCHEMBL8759234 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2MYCALDH1A1KDM4ENPC1 | |
| SCHEMBL17251283 | 0.80 | ACHE (0.56) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL6802081 | 0.79 | MCL1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHSD17B10MCL1 | |
| SCHEMBL6492271 | 0.79 | SMN1; SMN2 (0.84) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL8566031 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL25642614 | 0.78 | PRKAB2 (0.49) | SMN1; SMN2LCKFYNALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | SMN1; SMN2 1854/4885MYC 4037/4885LCK 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.