Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395234 | 0.82 | KDM4E (0.51) | AKR1C3AKR1C2PTGDR2KDM4EALDH1A1 | |
| SCHEMBL6804643 | 0.81 | SMN1; SMN2 (0.53) | AKR1C2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6489098 | 0.81 | SMN1; SMN2 (0.75) | AKR1C3AKR1C2BACE1PTGDR2KDM4E | |
| SCHEMBL6550819 | 0.81 | SMN1; SMN2 (0.57) | AKR1C3AKR1C2BACE1PTGDR2KDM4E | |
| SCHEMBL29979130 | 0.81 | SMN1; SMN2 (0.57) | AKR1C3AKR1C2BACE1PTGDR2KDM4E | |
| SCHEMBL3992911 | 0.81 | CFD (0.51) | AKR1C3AKR1C2BACE1TP53PTGDR2 | |
| SCHEMBL23768095 | 0.80 | XDH (0.49) | AKR1C3AKR1C2BACE1TP53PTGDR2 | |
| SCHEMBL6799953 | 0.80 | RXRA (0.55) | AKR1C3AKR1C2BACE1KDM4EALDH1A1 | |
| SCHEMBL8427571 | 0.80 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL3294513 | 0.79 | AKR1C3 (0.56) | AKR1C3AKR1C2BACE1PTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | AKR1C3 367/4885AKR1C2 503/4885BACE1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.