Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802096 | 0.91 | NPC1 (0.44) | TP53TSHRSMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL809394 | 0.85 | ALDH1A1 (0.59) | TP53TSHRSMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL6799120 | 0.83 | HDAC7 (0.49) | TSHRSMN1; SMN2ALDH1A1NPC1MEN1 | |
| SCHEMBL6492374 | 0.82 | DHODH (0.55) | TP53TSHRSMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL7554300 | 0.80 | ALDH1A1 (0.57) | TP53TSHRSMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL2558658 | 0.79 | AKR1C3 (0.51) | TP53TSHRSMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL6804716 | 0.79 | MCL1 (0.46) | TSHRSMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL6695209 | 0.79 | PRKAB2 (0.53) | TP53TSHRSMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL9762624 | 0.79 | MEN1 (0.46) | SMN1; SMN2ALDH1A1NPC1MEN1MAPT | |
| SCHEMBL11527291 | 0.78 | SMN1; SMN2 (0.49) | TP53TSHRSMN1; SMN2ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | TP53 4791/4885TSHR 1272/4885SMN1; SMN2 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.