Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGAV | P06756 | 11/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060984 | 0.91 | MAPT (0.37) | ITGB3ITGAVMAPTKDRRET | |
| SCHEMBL6807083 | 0.86 | CASP1 (0.37) | — | |
| SCHEMBL4641344 | 0.84 | ITGB3 (0.48) | ITGB3ITGAVMAPTKDRRET | |
| SCHEMBL4641533 | 0.81 | ITGB3 (0.42) | ITGB3ITGAVMAPTKDRRET | |
| SCHEMBL6807305 | 0.77 | SYK (0.36) | — | |
| SCHEMBL6806677 | 0.74 | CDK1 (0.48) | ITGB3ITGAV | |
| SCHEMBL6802305 | 0.73 | CDK1 (0.51) | — | |
| SCHEMBL6804208 | 0.73 | CDK1 (0.49) | ITGB3ITGAV | |
| SCHEMBL6804912 | 0.69 | ITGB3 (0.45) | ITGB3ITGAV | |
| SCHEMBL6811105 | 0.69 | CNR1 (0.44) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |