Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 9/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807305 | 0.90 | SYK (0.36) | CASP1DOT1L | |
| SCHEMBL6806739 | 0.86 | ITGB3 (0.40) | — | |
| SCHEMBL6807080 | 0.82 | ITGB3 (0.40) | DOT1L | |
| SCHEMBL4640795 | 0.79 | SLC29A1 (0.38) | DOT1L | |
| SCHEMBL7060984 | 0.77 | MAPT (0.37) | — | |
| SCHEMBL6802305 | 0.77 | CDK1 (0.51) | — | |
| SCHEMBL6806677 | 0.75 | CDK1 (0.48) | CASP1 | |
| SCHEMBL6807303 | 0.73 | JAK2 (0.36) | — | |
| SCHEMBL6806539 | 0.73 | BTK (0.43) | CASP1 | |
| SCHEMBL6804912 | 0.73 | ITGB3 (0.45) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |