SCHEMBL6806791

SCHEMBL6806791

COc1cc(NS(=O)(=O)c2ccccc2)c(O)cc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
KDM4E B2RXH2 3/20 0.54
HSD17B10 Q99714 2/20 0.54
GAA P10253 2/20 0.52
GFER P55789 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52
ERBB2 P04626 1/20 0.51
HSP90AA1 P07900 1/20 0.51
HSP90AB1 P08238 1/20 0.51
ALDH1A1 P00352 4/20 0.50
HPGD P15428 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
POLB P06746 1/20 0.49
HTT P42858 1/20 0.49
ACLY P53396 2/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
MCOLN2 Q8IZK6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27474093 0.87 HPGD (0.56) MEN1KMT2AKDM4EHSD17B10ALDH1A1
SCHEMBL6805770 0.85 MEN1 (0.58) MEN1KMT2AKDM4EHSD17B10GAA
SCHEMBL16274152 0.82 GAA (0.57) MEN1KMT2AHSD17B10GAAGFER
SCHEMBL6807890 0.81 KMT2A (0.54) MEN1KMT2AKDM4EHSD17B10GAA
SCHEMBL6806837 0.81 ALDH1A1 (0.66) MEN1KMT2AKDM4EHSD17B10GAA
SCHEMBL6806493 0.80 PKM (0.47) MEN1KMT2AKDM4EALDH1A1MAPK1
SCHEMBL1913762 0.79 ERBB2 (0.62) MEN1KMT2AKDM4EHSD17B10GAA
SCHEMBL25990827 0.78 MEN1 (0.48) MEN1KMT2AKDM4EHSD17B10GAA
SCHEMBL6808713 0.76 GAA (0.64) MEN1KMT2AHSD17B10GAAGFER
SCHEMBL11583293 0.76 MAPT (0.63) MEN1KMT2AALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed