Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807048 | 0.71 | CTSK (0.42) | KDM4EALDH1A1LMNAPKMHTT | |
| SCHEMBL6807050 | 0.71 | CTSK (0.42) | KDM4EALDH1A1LMNAPKMHTT | |
| SCHEMBL6206077 | 0.71 | CTSK (0.42) | KDM4EALDH1A1LMNAPKMHTT | |
| SCHEMBL6206079 | 0.71 | CTSK (0.42) | KDM4EALDH1A1LMNAPKMHTT | |
| SCHEMBL28736508 | 0.67 | HSD11B1 (0.54) | MMP13MMP9POLBKDM4EALDH1A1 | |
| SCHEMBL6810573 | 0.64 | ALDH1A1 (0.33) | ALDH1A1LMNAKMT2A | |
| SCHEMBL5105404 | 0.63 | ALOX5AP (0.42) | KDM4EALDH1A1LMNAPKMHTT | |
| SCHEMBL14131623 | 0.63 | ALOX5AP (0.42) | KDM4EALDH1A1LMNAPKMHTT | |
| SCHEMBL5983474 | 0.62 | CTSK (0.42) | SMYD3ELOVL6CTSK | |
| SCHEMBL4316467 | 0.62 | CTSK (0.42) | SMYD3ELOVL6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157828-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157828-A1 | Protease inhibitors | CTSK, MMP13, CTSZ | MMP13 2/4885MMP1 16/4885MMP9 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.