Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802803 | 0.72 | CTSS (0.41) | NPC1RAB9AITGB3ITGB1ITGAV | |
| SCHEMBL6803822 | 0.71 | SOAT2 (0.38) | NPC1RAB9AKDM4EGFERSMN1; SMN2 | |
| SCHEMBL6803515 | 0.71 | ITGB3 (0.39) | NPC1RAB9AITGB3ITGB1ITGAV | |
| SCHEMBL7181514 | 0.70 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2KDRITGB3 | |
| SCHEMBL9087858 | 0.70 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2KDRITGB3 | |
| SCHEMBL6802479 | 0.69 | CTSS (0.43) | NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10876725 | 0.69 | BCHE (0.61) | NPC1RAB9AKDM4EGFERSMN1; SMN2 | |
| SCHEMBL6802536 | 0.68 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1ITGB3 | |
| SCHEMBL6804384 | 0.67 | CTSS (0.41) | NPC1RAB9AITGB3ITGB1ITGAV | |
| SCHEMBL6799563 | 0.66 | KMT2A (0.48) | NPC1RAB9AKDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | NPC1 2721/4885RAB9A 1163/4885KDM4E 3172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.