Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214167 | 0.78 | KDM4E (0.46) | KDM4ELMNAALDH1A1RECQLHPGD | |
| SCHEMBL33732 | 0.78 | KDM4E (0.36) | KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL2266214 | 0.62 | KDM4E (0.41) | KDM4ELMNAALDH1A1RECQLHPGD | |
| SCHEMBL2267643 | 0.59 | KDM4E (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL2271752 | 0.59 | KDM4E (0.46) | KDM4ELMNAALDH1A1RECQLHPGD | |
| SCHEMBL5315996 | 0.59 | KDM4E (0.42) | KDM4EALDH1A1HPGD | |
| SCHEMBL2272571 | 0.59 | ALDH1A1 (0.33) | KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL2270814 | 0.57 | KDM4E (0.56) | KDM4EALDH1A1HPGD | |
| SCHEMBL2268691 | 0.56 | KDM4E (0.39) | KDM4ELMNAALDH1A1RECQLHPGD | |
| SCHEMBL2268724 | 0.56 | ALDH1A1 (0.33) | KDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6733539-B2 | HAIR DYES | L'OREAL S.A. (FR) | 2004-05-11 | — | — | US | claimed |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | claimed |
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | PLOS GREGORY (FR) | 2002-02-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | KRT18, PPOX, AOX1 | KDM4E 800/4885LMNA 1149/4885ALDH1A1 104/4885 |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | KRT18, PPOX, AOX1 | KDM4E 800/4885LMNA 1149/4885ALDH1A1 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.