Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366587 | 0.83 | SCN9A (0.56) | SCN9A | |
| SCHEMBL680289 | 0.82 | MCL1 (0.70) | SCN9AMCL1BCL2L1NPC1RAB9A | |
| SCHEMBL679785 | 0.82 | MCL1 (0.62) | SCN9AMCL1BCL2L1SCN3AHDAC8 | |
| SCHEMBL680286 | 0.82 | PGR (0.60) | SCN9AMCL1BCL2L1KMT2ANPC1 | |
| SCHEMBL680466 | 0.82 | EZH2 (0.54) | SCN9AMCL1BCL2L1L3MBTL1NPC1 | |
| SCHEMBL679782 | 0.81 | SCN9A (0.50) | SCN9AMCL1BCL2L1MEN1KMT2A | |
| SCHEMBL679703 | 0.81 | SCN9A (0.49) | PTPN1SCN9AMCL1BCL2L1MEN1 | |
| SCHEMBL680832 | 0.81 | PLA2G7 (0.55) | PTPN1SCN9APLA2G7 | |
| SCHEMBL678903 | 0.81 | BCL2L1 (0.52) | SCN9AMCL1BCL2L1MEN1KMT2A | |
| SCHEMBL678831 | 0.81 | BCL2L1 (0.52) | PTPN1SCN9AMCL1BCL2L1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |
| US-20120010207-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010207-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | PTPN1 404/4885SCN9A 13/4885PLA2G7 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.