SCHEMBL6808919

SCHEMBL6808919

CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)CC1(c2ccccc2)CCN(C)CC1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 8/20 0.50
UBE2M P61081 1/20 0.47
DCUN1D1 Q96GG9 1/20 0.47
SOAT2 O75908 2/20 0.41
ACAT1 P24752 1/20 0.41
P2RX7 Q99572 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765050 0.90 SOAT1 (0.51) SOAT1UBE2MDCUN1D1SOAT2ACAT1
SCHEMBL6803071 0.87 UBE2M (0.46) SOAT1UBE2MDCUN1D1SOAT2ACAT1
SCHEMBL11143056 0.79 ALDH1A1 (0.58) SOAT1UBE2MDCUN1D1SOAT2KMT2A
SCHEMBL6803622 0.78 NMBR (0.45) SOAT1UBE2MDCUN1D1SOAT2ACAT1
SCHEMBL9680743 0.78 SOAT1 (0.51) SOAT1SOAT2ACAT1KMT2AMEN1
SCHEMBL6803303 0.77 UBE2M (0.41) SOAT1UBE2MDCUN1D1SOAT2ACAT1
SCHEMBL9765058 0.76 TP53 (0.46) KMT2AMEN1TDP1LMNA
SCHEMBL6807653 0.75 SOAT1 (0.43) SOAT1UBE2MDCUN1D1SOAT2ACAT1
SCHEMBL6184564 0.75 SOAT1 (0.41) SOAT1UBE2MDCUN1D1SOAT2ACAT1
SCHEMBL9765049 0.74 SOAT2 (0.48) SOAT1SOAT2ACAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063643-A1 Bombesin antagonists PFIZER INC. 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063643-A1 Bombesin antagonists BRS3, NPSR1, GNRHR SOAT1 3334/4885UBE2M 3897/4885DCUN1D1 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.