Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943431 | 0.75 | PLA2G7 (0.45) | ALDH1A1ATMRAB9ANPC1SMN1; SMN2 | |
| Benzenemethanethiol SCHEMBL6808974 | 0.70 | PLA2G7 (0.41) | ALDH1A1ATMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20395222 | 0.68 | CYP2C19 (0.59) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL5935744 | 0.65 | CYP2C19 (0.52) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL26447128 | 0.63 | CYP2C19 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL10560722 | 0.62 | CYP2C19 (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL941161 | 0.61 | CYP1A2 (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL499117 | 0.61 | CYP2C19 (0.64) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL12624599 | 0.60 | CYP2C19 (0.49) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL5840786 | 0.60 | CYP2C19 (0.57) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | MMP9, MMP10, MMP3 | ALDH1A1 573/4885ATM 4778/4885RAB9A 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.