Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809307 | 0.94 | CHRM2 (0.31) | OPRM1 | |
| SCHEMBL11287401 | 0.71 | DNM1 (0.32) | OPRM1CA1 | |
| SCHEMBL6809310 | 0.69 | — | — | |
| SCHEMBL8517438 | 0.69 | OPRM1 (0.42) | OPRM1SPHK1CA1 | |
| SCHEMBL6753724 | 0.67 | — | — | |
| SCHEMBL1668247 | 0.67 | OPRM1 (0.33) | OPRM1SPHK1 | |
| SCHEMBL19171390 | 0.67 | — | — | |
| SCHEMBL8185810 | 0.66 | MAPT (0.46) | CA1 | |
| SCHEMBL6813934 | 0.65 | — | — | |
| SCHEMBL18746534 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8784791-B2 | Method for preparing water-soluble polymer derivatives bearing an N-succinimidyl ester | NEKTAR THERAPEUTICS (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130231490-A1 | METHOD FOR PREPARING WATER-SOLUBLE POLYMER DERIVATIVES BEARING AN N-SUCCINIMIDYL ESTER | NEKTAR THERAPEUTICS (US) | 2013-09-05 | — | — | US | disclosed |
| US-20120209027-A1 | Method for Preparing Water-Soluble Polymer Derivatives Bearing a Terminal Carboxylic Acid | NEKTAR THERAPEUTICS (US) | 2012-08-16 | — | — | US | disclosed |
| US-8182801-B2 | Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid | NEKTAR THERAPEUTICS (US) | 2012-05-22 | — | — | US | disclosed |
| US-20090264600-A1 | Method for Preparing Water-Soluble Polymer Derivatives Bearing a Terminal Carboxylic Acid | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120209027-A1 | Method for Preparing Water-Soluble Polymer Derivatives Bearing a Terminal Carboxylic Acid | SI, APEH, PGA5 | OPRM1 1595/4885SPHK1 3372/4885CA1 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.