Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365173 | 0.96 | MAOB (0.61) | HDAC3HDAC1HDAC2NCOR2MAOB | |
| Diethylamine SCHEMBL16239601 | 0.90 | HDAC3 (0.58) | HDAC3HDAC1HDAC2NCOR2MAOB | |
| SCHEMBL680720 | 0.89 | EZH2 (0.58) | HDAC3HDAC1HDAC2NCOR2MAOB | |
| SCHEMBL364237 | 0.88 | BCL2L1 (0.72) | HDAC3HDAC1HDAC2NCOR2MAOB | |
| SCHEMBL364340 | 0.84 | RXRA (0.62) | HDAC3HDAC1HDAC2NCOR2NPC1 | |
| SCHEMBL16239768 | 0.84 | ALDH1A1 (0.70) | NPC1RAB9ASMN1; SMN2HPGDBCL2L1 | |
| SCHEMBL365645 | 0.84 | ALDH1A1 (0.70) | NPC1RAB9ASMN1; SMN2HPGDBCL2L1 | |
| SCHEMBL365210 | 0.83 | MAOA (0.63) | MAOBNPC1RAB9ASMN1; SMN2NR4A2 | |
| SCHEMBL366812 | 0.83 | MAOB (0.63) | HDAC1HDAC2MAOBNR4A2BCL2L1 | |
| SCHEMBL366081 | 0.83 | MAOA (0.63) | MAOBNPC1RAB9ASMN1; SMN2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |
| US-20120010207-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010207-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | HDAC3 443/4885HDAC1 493/4885HDAC2 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.