Perchlorate

Perchlorate

SCHEMBL6809683

COc1ccc(-c2ccc3ccccc3[o+]2)cc1.[O-][Cl+3]([O-])([O-])[O-]

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.42
ABCB1 P08183 1/20 0.42
BCR P11274 1/20 0.42
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
HTT P42858 2/20 0.41
MITF O75030 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
PTGS2 P35354 1/20 0.40
MAPT P10636 2/20 0.38
LTA4H P09960 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11860130 0.94 NPC1 (0.46) ABL1ABCB1BCRNPC1RAB9A
Perchlorate SCHEMBL11867107 0.83 RAB9A (0.36) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
Perchlorate SCHEMBL11876177 0.82 CYP1A2 (0.46) ABL1ABCB1BCRNPC1RAB9A
Perchlorate SCHEMBL11873006 0.81 NPC1 (0.42) ABL1ABCB1BCRNPC1RAB9A
Perchlorate SCHEMBL11877376 0.80 PTGS2 (0.37) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
Perchlorate SCHEMBL11870697 0.80 MEN1 (0.38) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
Perchlorate SCHEMBL11864779 0.77 HSD17B1 (0.40) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
Perchlorate SCHEMBL6810519 0.77 ALDH1A1 (0.41) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
Perchlorate SCHEMBL7741224 0.76 ABL1 (0.50) ABL1ABCB1BCRNPC1RAB9A
Perchlorate SCHEMBL9174324 0.75 KDM4E (0.45) ABL1ABCB1BCRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3953433-A REACTION PRODUCT COMPRISING BENZOPYRYLIUM SALT AND BENZOPYRAN RICOH CO., LTD. (JA) 1976-04-27 US claimed
US-6807138-B1 Light drive TRANSPECTRAL SYSTEM LLC 2004-10-19 US disclosed