Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251336 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KMT2ALMNAPOLBMAPK1 | |
| SCHEMBL20564117 | 0.85 | TSHR (0.47) | TSHRRECQLCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL6782433 | 0.84 | TSHR (0.42) | TSHRRECQLCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7301501 | 0.82 | TSHR (0.41) | TSHRRECQLCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1970982 | 0.82 | TSHR (0.41) | TSHRRECQLCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL24242177 | 0.82 | TSHR (0.41) | TSHRRECQLALDH1A1RAB9AMAPT | |
| SCHEMBL7308023 | 0.82 | TSHR (0.41) | TSHRRECQLCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7302799 | 0.82 | TSHR (0.41) | TSHRRECQLCYP3A4CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15993297 | 0.81 | TSHR (0.40) | TSHRRECQLCYP2C19ALDH1A1RAB9A | |
| SCHEMBL23135867 | 0.81 | TSHR (0.43) | TSHRRECQLCYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686348-B2 | N-HYDROXY-6-((2-(4-PYRIDYL)-1-BENZOFURAN-5-YL)SULPHONYL)-4,5,6,7 -TETRAHYDRO(2,3-C)-PYRIDINE-5-CARBOXAMIDE FOR EXAMPLE; TREATING RHEUMATIC DISEASES, CANCER | LES LABORATOIRES SERVIER (FR) | 2004-02-03 | — | — | US | disclosed |
| US-20020137744-A1 | Metalloprotease inhibitors | LES LABORATOIRES SERVIER (FR) | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137744-A1 | Metalloprotease inhibitors | MMP9, MMP3, MMP2 | TSHR 1605/4885RECQL 3320/4885CYP3A4 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.