Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817166 | 0.91 | MAOB (0.59) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6358257 | 0.85 | MAOB (0.58) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6812774 | 0.84 | NR4A2 (0.62) | MAOBMAOAMEN1KMT2ALMNA | |
| SCHEMBL8991408 | 0.80 | MAOB (0.79) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6352882 | 0.77 | AKR1C2 (0.55) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6349305 | 0.76 | AKR1C2 (0.66) | MAOBMEN1KMT2AMAPTLMNA | |
| SCHEMBL28317001 | 0.76 | MAOB (0.79) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6817692 | 0.75 | NR4A2 (0.63) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL28232014 | 0.74 | MAOB (0.73) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6030587 | 0.73 | GPR132 (0.59) | MAOBMAOAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |