Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PYGL | P06737 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352882 | 0.92 | AKR1C2 (0.55) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6349305 | 0.91 | AKR1C2 (0.66) | MAOBMEN1KMT2AMAPTLMNA | |
| SCHEMBL6351828 | 0.86 | PTGES (0.62) | MEN1KMT2AMAPTAKR1C2AKR1C1 | |
| SCHEMBL4213146 | 0.85 | AKR1C2 (0.61) | MAOBMEN1KMT2AMAPTLMNA | |
| SCHEMBL6812445 | 0.85 | MAOB (0.58) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL4208795 | 0.84 | NR4A2 (0.62) | MAOBMAPTAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6359602 | 0.83 | AKR1C2 (0.55) | MEN1KMT2AMAPTLMNAAKR1C2 | |
| SCHEMBL6352508 | 0.82 | AKR1C2 (0.70) | MEN1KMT2AMAPTPYGLAKR1C2 | |
| SCHEMBL4206544 | 0.82 | NR4A2 (0.64) | MAOBMAPTAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL8991408 | 0.80 | MAOB (0.79) | MAOBMAOAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MAOB 2949/4885MAOA 1903/4885MEN1 3274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.