Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 5/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.55 |
| ▸ | PYGL | P06737 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.46 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358257 | 0.92 | MAOB (0.58) | AKR1C2AKR1C1PYGLMEN1KMT2A | |
| SCHEMBL6349305 | 0.83 | AKR1C2 (0.66) | AKR1C2AKR1C1PYGLMEN1KMT2A | |
| SCHEMBL6349641 | 0.82 | PLK1 (0.60) | AKR1C2AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL6352508 | 0.80 | AKR1C2 (0.70) | AKR1C2AKR1C1PYGLMEN1KMT2A | |
| SCHEMBL6349385 | 0.80 | AKR1C2 (0.71) | AKR1C2AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL6351828 | 0.79 | PTGES (0.62) | AKR1C2AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL6353212 | 0.79 | AKR1C2 (0.66) | AKR1C2AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL4213146 | 0.77 | AKR1C2 (0.61) | AKR1C2AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL6346862 | 0.77 | AKR1C2 (0.80) | AKR1C2AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL6350022 | 0.77 | AKR1C2 (0.72) | AKR1C2AKR1C1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885PYGL 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.