Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924687 | 0.83 | GALK1 (0.57) | TP53BCAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6359657 | 0.79 | MAPT (0.70) | TP53ALDH1A1KDM4EHPGDCA2 | |
| SCHEMBL6835786 | 0.79 | LMNA (0.50) | TP53ALDH1A1KDM4ECA2CA12 | |
| SCHEMBL6353430 | 0.78 | MAPT (0.57) | ALDH1A1KDM4EHPGDCA2TSHR | |
| SCHEMBL6833112 | 0.78 | KDM4E (0.57) | TP53BCAT1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL6349388 | 0.78 | MAPT (0.52) | ALDH1A1KDM4EHPGDCA2CA12 | |
| SCHEMBL6357140 | 0.77 | MEN1 (0.60) | ALDH1A1KDM4ECA2MAPTNPC1 | |
| SCHEMBL6832994 | 0.76 | HIF1A (0.46) | TP53ALDH1A1KDM4ECA2CA12 | |
| SCHEMBL6835702 | 0.75 | MAPT (0.47) | TP53ALDH1A1KDM4EHPGDCA2 | |
| SCHEMBL5866917 | 0.74 | TP53 (0.74) | TP53BCAT1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | TP53 2331/4885BCAT1 197/4885ALDH1A1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.