Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.48 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835826 | 0.85 | KDM4E (0.61) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL6834022 | 0.83 | NPC1 (0.55) | BCAT1NPC1RAB9ANHERF1 | |
| SCHEMBL6359657 | 0.81 | MAPT (0.70) | KDM4EMAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL6709121 | 0.80 | KDM4E (0.50) | KDM4EMAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL6834052 | 0.79 | KMT2A (0.51) | KDM4EMAPTNPC1RAB9APOLB | |
| SCHEMBL6707805 | 0.79 | KDM4E (0.49) | KDM4EMAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL6834101 | 0.78 | NHERF1 (0.56) | NHERF1 | |
| SCHEMBL6353430 | 0.78 | MAPT (0.57) | KDM4EMAPTALDH1A1GAAPOLB | |
| SCHEMBL6834270 | 0.78 | FLT3 (0.50) | KDM4EALDH1A1NPC1RAB9APDGFRB | |
| SCHEMBL6814022 | 0.78 | TP53 (0.53) | KDM4EMAPTALDH1A1NPSR1BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | KDM4E 1240/4885MAPT 4759/4885ALDH1A1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.