Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814146 | 0.90 | FPR1 (0.38) | MEN1KMT2ALMNATRPA1MAPK14 | |
| SCHEMBL6484094 | 0.89 | LMNA (0.42) | MEN1KMT2ALMNATRPA1FPR1 | |
| SCHEMBL6814150 | 0.83 | TRPA1 (0.51) | TRPA1MAPK14 | |
| SCHEMBL6484773 | 0.74 | MEN1 (0.41) | MEN1KMT2ALMNAFPR1FPR2 | |
| Hydrochloric Acid SCHEMBL7021998 | 0.69 | TRPA1 (0.41) | MEN1KMT2ATRPA1KDM4E | |
| SCHEMBL6488185 | 0.68 | TRPA1 (0.53) | LMNATRPA1RXFP1 | |
| SCHEMBL6485436 | 0.67 | CNR2 (0.40) | MEN1KMT2ALMNAMAPK14FPR1 | |
| SCHEMBL6476120 | 0.67 | TRPA1 (0.54) | LMNATRPA1RXFP1 | |
| SCHEMBL6818733 | 0.66 | ROCK2 (0.46) | MEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL6486582 | 0.65 | MAPT (0.46) | MEN1KMT2ALMNATRPA1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |