Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811045 | 0.82 | NOS1 (0.41) | ADORA1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL6819013 | 0.82 | NOS1 (0.56) | ADORA1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL21852751 | 0.70 | ALDH1A1 (0.67) | ADORA1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL10456274 | 0.69 | NOS1 (0.43) | ADORA1KDM4ELMNATDP1NOS1 | |
| SCHEMBL6815719 | 0.69 | CYP1A2 (0.43) | ALDH1A1KDM4ELMNATDP1NOS1 | |
| SCHEMBL14525866 | 0.68 | ALDH1A1 (0.64) | ADORA1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL14983461 | 0.67 | DHFR (0.56) | ADORA1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL12067539 | 0.67 | DHFR (0.56) | ADORA1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL12131238 | 0.66 | ALDH1A1 (0.53) | ADORA1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL30696045 | 0.66 | ALDH1A1 (0.53) | ADORA1ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144412-B1 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2004-09-29 | — | — | EP | claimed |