Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819013 | 0.84 | NOS1 (0.56) | NOS1MEN1KMT2APOLBKDM4E | |
| SCHEMBL6814243 | 0.82 | ADORA1 (0.48) | NOS1MEN1KMT2ARXFP1KDM4E | |
| SCHEMBL6814345 | 0.77 | KDM4E (0.43) | NOS1MEN1KMT2APOLBRXFP1 | |
| SCHEMBL6815719 | 0.77 | CYP1A2 (0.43) | NOS1KDM4ELMNATRIM58ALDH1A1 | |
| SCHEMBL10456274 | 0.71 | NOS1 (0.43) | NOS1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL6811031 | 0.68 | PIK3CG (0.64) | NOS1MEN1KMT2APOLBKDM4E | |
| SCHEMBL6814751 | 0.68 | TRIM58 (0.31) | TRIM58 | |
| SCHEMBL29913237 | 0.67 | HEXA (0.50) | MEN1KMT2AKDM4ELMNATRIM58 | |
| SCHEMBL6811076 | 0.66 | NUDT1 (0.45) | NOS1MEN1KMT2APOLBKDM4E | |
| SCHEMBL6811620 | 0.66 | NUDT1 (0.45) | NOS1MEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144412-B1 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2004-09-29 | — | — | EP | claimed |