Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814261 | 0.91 | MEN1 (0.33) | KDM5AKDM5BKDM4CKDM4EMEN1 | |
| SCHEMBL6477879 | 0.90 | KDM5A (0.33) | KDM5AKDM5BKDM4CALDH1A1 | |
| SCHEMBL6814257 | 0.82 | NAMPT (0.39) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6664689 | 0.73 | PSEN1 (0.43) | KDM5AKDM5BKDM4CKDM4EMEN1 | |
| SCHEMBL6486635 | 0.69 | P2RY14 (0.32) | ALDH1A1 | |
| SCHEMBL6477074 | 0.69 | CES2 (0.33) | KDM5AKDM5BKDM4CALDH1A1 | |
| SCHEMBL6669268 | 0.68 | ROCK2 (0.38) | KDM5AKDM5BKDM4CMEN1KMT2A | |
| SCHEMBL6813861 | 0.66 | CES2 (0.36) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6484477 | 0.65 | HCAR3 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL6482492 | 0.64 | DAO (0.34) | KDM5AKDM5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |