Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15779329 | 0.90 | CTSK (0.40) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL6245269 | 0.83 | CA1 (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL12954710 | 0.82 | CTSK (0.43) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL14608213 | 0.81 | PPARA (0.50) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL4854926 | 0.81 | PPARA (0.50) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL1022397 | 0.81 | PPARA (0.50) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL6810313 | 0.80 | CTSS (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL27723684 | 0.77 | CTSK (0.52) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL26121244 | 0.77 | CTSS (0.49) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL26119972 | 0.77 | CTSS (0.49) | PPARAPPARGCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040249187-A1 | Method for producing chiral amino acid derivatives | BAYER CHEMICALS AG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249187-A1 | Method for producing chiral amino acid derivatives | ADH5, AADAT, NOS2 | PPARA 910/4885PPARG 2512/4885CTSS 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.