Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815937 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL6814520 | 0.87 | PTPN1 (0.53) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL6818227 | 0.87 | MAPT (0.50) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL92482 | 0.84 | CNR2 (0.64) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL6818569 | 0.84 | L3MBTL1 (0.58) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL6818570 | 0.83 | CNR2 (0.53) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL6818455 | 0.82 | CNR2 (0.69) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL6813643 | 0.81 | CNR2 (0.68) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL71318 | 0.81 | BRD4 (0.67) | ALDH1A1HPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL31039820 | 0.80 | RAB9A (0.69) | ALDH1A1HPGDHSD17B10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ALDH1A1 170/4885HPGD 1657/4885HSD17B10 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.