Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815411 | 1.00 | MMP9 (0.45) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6818700 | 0.85 | HPN (0.45) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6818706 | 0.85 | HPN (0.45) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6814338 | 0.84 | CTSS (0.42) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6814340 | 0.84 | CTSS (0.42) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6819150 | 0.81 | CTSL (0.43) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6818927 | 0.81 | CTSL (0.43) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6819859 | 0.81 | MMP2 (0.51) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6819854 | 0.81 | MMP2 (0.51) | MMP9MMP8MMP2MMP1CTSL | |
| SCHEMBL6818472 | 0.80 | MMP2 (0.49) | MMP9MMP8MMP2MMP1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |