Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821018 | 0.89 | UTS2R (0.50) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL6817310 | 0.88 | HTR7 (0.46) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL6817354 | 0.84 | HTR7 (0.48) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL6820722 | 0.84 | UTS2R (0.52) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL6820726 | 0.81 | HTR7 (0.52) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL6817351 | 0.78 | UTS2R (0.50) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL6817280 | 0.78 | HTR7 (0.45) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL6820977 | 0.78 | HTR6 (0.53) | HTR7UTS2RDRD2HTR1BHTR1A | |
| SCHEMBL6823545 | 0.77 | UTS2R (0.41) | HTR7UTS2RDRD1DRD2DRD4 | |
| SCHEMBL3558434 | 0.75 | HTR7 (0.45) | HTR7UTS2RHTR1BKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |