Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817354 | 0.88 | HTR7 (0.48) | HTR6HTR7UTS2RDRD2HTR1B | |
| SCHEMBL6817351 | 0.86 | UTS2R (0.50) | HTR6HTR7UTS2RDRD2 | |
| SCHEMBL6820726 | 0.86 | HTR7 (0.52) | HTR6HTR7UTS2RDRD2HTR1B | |
| SCHEMBL6821057 | 0.85 | HTR6 (0.69) | HTR6PLA2G2A | |
| SCHEMBL3256595 | 0.84 | HTR6 (0.74) | HTR6HTR7HTR1ADRD2HTR1D | |
| SCHEMBL6820735 | 0.78 | PLA2G2A (0.46) | HTR6UTS2RPLA2G2AHTR2A | |
| SCHEMBL6817341 | 0.78 | HTR7 (0.48) | HTR6HTR7UTS2RHTR1ADRD2 | |
| SCHEMBL3559586 | 0.77 | HTR6 (0.56) | HTR6HTR7HTR1ADRD2HTR1D | |
| SCHEMBL6821035 | 0.77 | HTR6 (0.52) | HTR6HTR7PLA2G2AHTR1ADRD2 | |
| SCHEMBL6821018 | 0.76 | UTS2R (0.50) | HTR7UTS2RDRD2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |