Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | WRN | Q14191 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036444 | 0.79 | SLC1A2 (0.32) | — | |
| SCHEMBL2030884 | 0.77 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL16694971 | 0.76 | — | — | |
| SCHEMBL2607935 | 0.75 | MGLL (0.39) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL1970949 | 0.70 | ALDH1A1 (0.32) | ALDH1A1HPGDBLM | |
| SCHEMBL9516281 | 0.69 | ALDH1A1 (0.33) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL3173583 | 0.69 | TSHR (0.41) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28884160 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28212807 | 0.69 | MGLL (0.35) | ALDH1A1BLM | |
| SCHEMBL2835666 | 0.68 | MGLL (0.38) | ALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2695003-B1 | COMPOSITION FOR FORMING A CONTACT LENS | NOVARTIS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| EP-2695003-A1 | COMPOSITION FOR FORMING A CONTACT LENS | Novartis AG (CH) | 2014-02-12 | — | — | EP | disclosed |
| US-8618187-B2 | Composition for forming a contact lens | NOVARTIS AG (CH) | 2013-12-31 | — | — | US | disclosed |
| US-20120252921-A1 | COMPOSITION FOR FORMING A CONTACT LENS | ALCON INC. (CH) | 2012-10-04 | — | — | US | disclosed |
| WO-2012130956-A1 | COMPOSITION FOR FORMING A CONTACT LENS | NOVARTIS AG (CH) | 2012-10-04 | — | — | WO | disclosed |
| EP-1044390-B1 | PROGRAMMABLE CORRECTIVE LENS | NOVARTIS AG (CH) | 2004-06-30 | — | — | EP | disclosed |
| US-6342570-B1 | COPOLYMERIZING VINYL LACTAM AND VINYL MONOMER; METERING IN SECOND MONOMER MIXTURE; STATISTICALLY DISTRIBUTED BUILDING BLOCKS IN ACCORD WITH LEWIS-MAYO EQUATION; CURABLE | NOVARTIS AG (CH) | 2002-01-29 | — | — | US | disclosed |
| CN-1285927-A | Programmable Corrective Lens | NOVARTIS AG (CH) | 2001-02-28 | — | — | CN | disclosed |
| CN-1283280-A | Actively controllable multifocal lens | NOVARTIS AG (CH) | 2001-02-07 | — | — | CN | disclosed |
| US-6139146-A | Programmable corrective lenses | NOVARTIS AG (CH) | 2000-10-31 | — | — | US | disclosed |
| EP-1044389-A2 | ACTIVELY CONTROLLABLE MULTIFOCAL LENS | Novartis AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| EP-1044390-A1 | PROGRAMMABLE CORRECTIVE LENS | Novartis AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| US-5997140-A | Actively controllable multifocal lens | NOVARTIS AG (CH) | 1999-12-07 | — | — | US | disclosed |
| US-5936052-A | Cross-linkable copolymers and hydrogels | CIBA VISION CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1999034244-A1 | PROGRAMMABLE CORRECTIVE LENS | NOVARTIS AG (CH) | 1999-07-08 | — | — | WO | disclosed |
| WO-1999034239-A2 | ACTIVELY CONTROLLABLE MULTIFOCAL LENS | NOVARTIS AG (CH) | 1999-07-08 | — | — | WO | disclosed |
| EP-0655470-B1 | Cross-linkable copolymers and hydrogels | NOVARTIS AG (CH) | 1999-05-12 | — | — | EP | disclosed |
| US-5712356-A | Cross-linkable copolymers and hydrogels | CIBA VISION CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0655470-A1 | Cross-linkable copolymers and hydrogels | CIBA-GEIGY AG (CH) | 1995-05-31 | — | — | EP | disclosed |