Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320670 | 0.88 | KMO (0.36) | HSD11B1F2RL3 | |
| SCHEMBL9789795 | 0.82 | HSD11B1 (0.46) | HSD11B1CRHR1HSP90AA1HSP90AB1LMNA | |
| SCHEMBL7501165 | 0.81 | MAPT (0.41) | LMNA | |
| SCHEMBL7588842 | 0.81 | L3MBTL1 (0.32) | — | |
| SCHEMBL6674197 | 0.80 | PDE4B (0.30) | — | |
| SCHEMBL6691871 | 0.80 | KMT2A (0.32) | F2RL3 | |
| SCHEMBL6287494 | 0.80 | SCN9A (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL6818668 | 0.76 | PDE4B (0.33) | CRHR1 | |
| SCHEMBL6671937 | 0.76 | PDE2A (0.31) | CRHR1 | |
| SCHEMBL6690722 | 0.76 | F2RL3 (0.34) | F2RL3CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897322-B2 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-1H-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | disclosed |
| US-6888003-B2 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| EP-1272486-B1 | METHOD FOR PRODUCING 7-(PYRAZOLE-3-YL) BENZOXAZOLES | BASF AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
| EP-1358164-A1 | METHOD OF PRODUCING 1-ALKYL-3-ARYL-5-DIFLUOROMETHOXY-1H-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-05 | — | — | EP | disclosed |
| US-20030050477-A1 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | US | disclosed |
| WO-2002055504-A1 | METHOD OF PRODUCING 1-ALKYL-3-ARYL-5-DIFLUOROMETHOXY-1H-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | CYP2E1, CYP2F1, CYP1A1 | HSD11B1 77/4885F2RL3 2521/4885CRHR1 789/4885 |
| US-20030050477-A1 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | F7, F9, TPO | HSD11B1 2263/4885F2RL3 3099/4885CRHR1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.