Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636801 | 0.81 | MAPT (0.65) | ALDH1A1PTPN1BRD4TSHRMAPT | |
| SCHEMBL1179236 | 0.80 | ALDH1A1 (0.62) | ALDH1A1PTPN1BRD4TSHRKDM4E | |
| SCHEMBL2818916 | 0.80 | ALDH1A1 (0.62) | ALDH1A1PTPN1BRD4TSHRKDM4E | |
| SCHEMBL3413937 | 0.80 | NPC1 (0.63) | ALDH1A1PTPN1BRD4MAPTHPGD | |
| SCHEMBL70022 | 0.80 | ALDH1A1 (0.62) | ALDH1A1PTPN1BRD4TSHRKDM4E | |
| SCHEMBL71299 | 0.77 | ALDH1A1 (1.00) | ALDH1A1PTPN1MAPTHPGDRECQL | |
| SCHEMBL31039820 | 0.76 | RAB9A (0.69) | ALDH1A1TSHRKDM4EMAPTHPGD | |
| SCHEMBL21523664 | 0.76 | SCD5 (0.60) | ALDH1A1PTPN1BRD4TSHRKDM4E | |
| SCHEMBL29775908 | 0.76 | SCD5 (0.58) | ALDH1A1PTPN1BRD4TSHRKDM4E | |
| SCHEMBL6818423 | 0.76 | SCD5 (0.58) | ALDH1A1PTPN1BRD4TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ALDH1A1 170/4885PTPN1 3166/4885BRD4 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.