Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819150 | 0.86 | CTSL (0.43) | SLC1A3SLC1A2SLC1A1CTSLCTSS | |
| SCHEMBL6818927 | 0.86 | CTSL (0.43) | SLC1A3SLC1A2SLC1A1CTSLCTSS | |
| Benzene SCHEMBL6818872 | 0.84 | CTSL (0.48) | CTSLCTSSCTSKCA1CA2 | |
| SCHEMBL6814773 | 0.81 | MMP9 (0.47) | MMP2MMP9MMP8MMP1ADAMTS4 | |
| SCHEMBL6093215 | 0.79 | ITGB3 (0.67) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6668234 | 0.79 | ITGB3 (0.67) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5502396 | 0.79 | ITGB3 (0.67) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL805209 | 0.78 | MMP2 (0.52) | CTSLCTSSCTSKCA1CA2 | |
| SCHEMBL16203423 | 0.78 | MMP2 (0.52) | CTSLCTSSCTSKCA1CA2 | |
| SCHEMBL20214369 | 0.78 | CYP2A6 (0.50) | CTSLCTSSCTSKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |