SCHEMBL681901

SCHEMBL681901

CC(C)(CO)COC(=O)OCC(C)(C)CO

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
SERPINE1 P05121 1/20 0.35
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
DGAT1 O75907 1/20 0.31
NUDT1 P36639 3/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28447036 0.89 ALDH1A1 (0.32) ALDH1A1SERPINE1TP53CYP3A4MAPK1
SCHEMBL28459203 0.85 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8863309 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1SMN1; SMN2LMNA
SCHEMBL28460064 0.82
SCHEMBL27686927 0.82 SERPINE1 (0.34) ALDH1A1SERPINE1TP53CYP3A4MAPK1
SCHEMBL2721208 0.82 SERPINE1 (0.34) ALDH1A1SERPINE1KDM4ETP53CYP3A4
SCHEMBL5692427 0.82 ALDH1A1 (0.42) ALDH1A1SERPINE1KDM4EPKMTP53
SCHEMBL8863777 0.81 NAAA (0.47) ALDH1A1LMNA
SCHEMBL28449366 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL4698759 0.80 LMNA (0.52) ALDH1A1SERPINE1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2712880-B1 POLYCARBONATE COPOLYMER HAVING HIGH FLUIDITY, METHOD FOR PRODUCING AROMATIC POLYCARBONATE RESIN HAVING HIGH MOLECULAR WEIGHT, AND AROMATIC POLYCARBONATE COMPOUND MITSUBISHI GAS CHEMICAL CO (JP) 2026-01-21 EP disclosed
EP-3438153-B1 HIGH MOLECULAR WEIGHT AROMATIC POLYCARBONATE RESIN MANUFACTURING METHOD MITSUBISHI GAS CHEMICAL CO (JP) 2024-06-12 EP disclosed
CN-109791381-B Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same 三菱化学株式会社 2023-03-10 CN disclosed
CN-110167995-B Plasticized PVC compounds having surface-modified macromolecules and articles made therefrom 界面生物公司 2022-07-01 CN disclosed
CN-108699229-B Process for producing high molecular weight aromatic polycarbonate resin 三菱瓦斯化学株式会社 2021-09-17 CN disclosed
US-11021571-B2 Manufacturing method for high molecular weight aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-06-01 US disclosed
US-10927216-B2 Manufacturing method for high molecular weight aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-23 US disclosed
US-10894860-B2 High molecular weight aromatic polycarbonate resin manufacturing method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-01-19 US disclosed
US-10884348-B2 Electrophotographic photoreceptor, and electrophotographic cartridge and image forming apparatus including same MITSUBISHI CHEMICAL CORPORATION (JP) 2021-01-05 US disclosed
US-20200216611-A1 MANUFACTURING METHOD FOR HIGH MOLECULAR WEIGHT AROMATIC POLYCARBONATE RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-07-09 US disclosed
US-8178620-B2 Surface modifying macromolecules with high degradation temperatures and uses thereof INTERFACE BIOLOGICS INC. (CA) 2012-05-15 US disclosed
US-20120027342-A1 CATION-POLYMERIZABLE RESIN COMPOSITION AND CURED PRODUCT THEREOF DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
US-8071683-B2 Surface modifying macromolecules with high degradation temperatures and uses thereof INTERFACE BIOLOGICS INC. (CA) 2011-12-06 US disclosed
US-20110271961-A1 SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF INTERFACE BIOLOGICS INC. (CA) 2011-11-10 US disclosed
US-20110207893-A1 THERMALLY STABLE BIURET AND ISOCYANURATE BASED SURFACE MODIFYING MACROMOLECULES AND USES THEREOF INTERFACE BIOLOGIS INC. (CA) 2011-08-25 US disclosed
US-20080228253-A1 Surface modifying macromolecules with high degradation temperatures and uses thereof Evonik Canada Inc. (CA) 2008-09-18 US disclosed
US-5527968-A Process for the production of modified acrylic monomers NIPON PAINT CO., LTD. (JP) 1996-06-18 US disclosed
US-5446110-A Carbonate modified polyester polyol NIPPON PAINT CO., LTD. (JP) 1995-08-29 US disclosed
US-4199495-A Thiolcarbonate ester stabilizers ARGUS CHEMICAL CORP. (US) 1980-04-22 US disclosed
US-4041018-A FOR INJECTION MOLDINGS OR EXTRUDED PIPES, FILMS, AND FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207893-A1 THERMALLY STABLE BIURET AND ISOCYANURATE BASED SURFACE MODIFYING MACROMOLECULES AND USES THEREOF INMT, BHMT, B2M ALDH1A1 373/4885SERPINE1 1352/4885KDM4E 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.